Phix Sleep - Scientific Research

Magnesium | Lemon Balm | GABA | Sour Jujube

Magnesium

Selected references:

• Chronopathological forms of magnesium depletion with hypofunction or with hyperfunction of the biological clock.
  Magnes Res. 2002 Dec;15(3-4):263-8, Durlach J, Pagès N, Bac P, Bara M, Guiet-Bara A, Agrapart C., SDRM, Université Pierre et Marie Curie Paris V, F-75252 Paris, France.
• Magnesium therapy for periodic leg movements-related insomnia and restless legs syndrome.
  An open pilot study.; Sleep. 1998 Aug 1;21(5):501-5, Hornyak M, Voderholzer U, Hohagen F, Berger M, Riemann D., Department of Psychiatry and Psychotherapy, Albert-Ludwigs-University, Freiburg, Germany.

Lemon Balm

Selected references:

• A combination of valerian and lemon balm is effective in the treatment of restlessness and dyssomnia in children.
  Phytomedicine. 2006 Jun;13(6):383-7. Epub 2006 Feb 17, Müller SF, Klement S. Dr. Willmar Schwabe Pharmaceuticals, Karlsruhe, Germany.
• Attenuation of laboratory-induced stress in humans after acute administration of Melissa officinalis (Lemon Balm).
  Psychosom Med. 2004 Jul-Aug;66(4):607-13, Kennedy DO, Little W, Scholey AB. Human Cognitive Neuroscience Unit, Division of Psychology, University of Northumbria, Newcastle upon Tyne NE1 8ST, UK.

GABA

Selected references:

• Relaxation and immunity enhancement effects of gamma-aminobutyric acid (GABA) administration in humans.
  Biofactors. 2006;26(3):201-8, Abdou AM, Higashiguchi S, Horie K, Kim M, Hatta H, Yokogoshi H., Department of Research and Development, Pharma Foods International Co. Ltd., Kyoto, Japan.

Sour jujube

Selected references:

• Cyclopeptide alkaloid fraction from Zizyphi Spinosi Semen enhances pentobarbital-induced sleeping behaviors.
  J Ethnopharmacol. 2008 May 8;117(2):318-24. Epub 2008 Feb 13, Ma Y, Han H, Nam SY, Kim YB, Hong JT, Yun YP, Oh KW., College of Veterinary Medicine, Chungbuk National University, Cheongju 361-763, South Korea.
• Separation and purification of saponins from Semen Ziziphus jujuba and their sedative and hypnotic effects.
  J Pharm Pharmacol. 2007 Aug;59(8):1175-80, Jiang JG, Huang XJ, Chen J. College of Food and Bioengineering, South China University of Technology, Guangzhou, 510640, China.